Personalizing evidence-based primary prevention with aspirin: individualized risks and patient preference.
نویسندگان
چکیده
One of the unfortunate side consequences of evidencebased medicine (EBM) is that sometimes there is no escaping how small the benefit of any individual treatment may seem. In the “days of the giants,” doctors saved lives; now we can consult league tables that bloodlessly inform us how many patients—10, 50, or 200—must receive a treatment to avert even a single bad outcome,1 EBM’s venerable number needed to treat.
منابع مشابه
A Proposal for Personalizing National Guidelines
Background—Clinical practice guidelines that help clinicians and patients to understand the magnitude of expected individual risks and benefits would help with patient-centered decision-making and prioritization of care. We assessed the net benefit from taking daily aspirin to estimate the individual and public health implications of a more individualized decision-making approach. Methods and R...
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BACKGROUND Low-dose aspirin is an important therapeutic option in the secondary prevention of myocardial infarction (MI) and ischemic stroke, especially in light of its unique cost-effectiveness and widespread availability. In addition, based on the results of a number of large studies, aspirin is also widely used in the primary prevention of MI. This review provides an update of the available ...
متن کاملIndividual and population benefits of daily aspirin therapy: a proposal for personalizing national guidelines.
BACKGROUND Clinical practice guidelines that help clinicians and patients to understand the magnitude of expected individual risks and benefits would help with patient-centered decision-making and prioritization of care. We assessed the net benefit from taking daily aspirin to estimate the individual and public health implications of a more individualized decision-making approach. METHODS AND...
متن کاملBenefit-harm analysis and charts for individualized and preference-sensitive prevention: example of low dose aspirin for primary prevention of cardiovascular disease and cancer
BACKGROUND Clinical practice guidelines provide separate recommendations for different diseases that may be prevented or treated by the same intervention. Also, they commonly provide recommendations for entire populations but not for individuals. To address these two limitations, our aim was to conduct benefit-harm analyses for a wide range of individuals using the example of low dose aspirin f...
متن کاملIs aspirin useful in primary prevention?
There is no evidence that aspirin is effective for the primary prevention of cardiovascular events, although it may change the way that they present. Indeed, there is no evidence that long-term aspirin should be given to patients even with known cardiovascular disease. Theoretical arguments that aspirin can prevent cardiovascular events by reducing the propagation of thrombus are countered by e...
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ورودعنوان ژورنال:
- Circulation. Cardiovascular quality and outcomes
دوره 4 3 شماره
صفحات -
تاریخ انتشار 2011